Many airplanes (and other addons) use the Microsoft C ++ Redistributables 64bit.
These redistributables belong to Windows, but are not always installed.
They must be subsequently installed:Please also install if they appear as already installed.Sometimes the libraries are broken. Then they will be repaired automatically.
Here are the links to the most important C ++ 64bit Redistributables:
Please download and install (execute) one by one.
All c ++ redistributables can be found here:https://support.microsoft.com/en-us/help/2977003/the-latest-supported-visual-c-downloads
Often, the C ++ 64bit for 2017 is important.
Also .NET in version 3.5 and 4.6 or higher is sometimes important ... (See Windows Control Panel - Programs and Features)
Sometimes also the Java Runtimes are neccessary: